Differin Gel (Adapalene 0.1%) – 15g / 45g
Differin Gel is a dermatologist-developed, FDA-approved acne treatment featuring 0.1% Adapalene—a powerful retinoid. Originally available by prescription only, this breakthrough formula is now available over the counter. It penetrates deep into pores to prevent breakouts, unclog pores, and promote cell turnover, making it a trusted solution for treating and preventing acne. Unlike many harsh acne treatments, Differin is gentle enough for daily use while delivering visible, long-term results.
Key Benefits
- Treats and prevents blackheads, whiteheads, and pimples
- Unclogs pores and reduces inflammation
- Promotes skin cell turnover to reveal smoother, clearer skin
- Helps fade post-acne marks and dark spots
- Non-comedogenic and suitable for daily use
- Visible improvement in as little as 12 weeks
Key Ingredients & Their Benefits
| Ingredient | Benefit |
| Adapalene (0.1%) | A powerful retinoid that normalizes skin cell turnover and unclogs pores |
| Carbomer | Stabilizes the gel texture without clogging pores |
| Propylene Glycol | Enhances penetration and hydrates the skin |
| Methylparaben | Preserves product integrity |
| Purified Water | Acts as the base and hydrates the skin |
How to Use
- Cleanse skin thoroughly and pat dry.
- Apply a thin layer of Differin Gel once daily, preferably at night.
- Avoid applying on broken or irritated skin.
- Follow with a gentle moisturizer to prevent dryness.
- Always wear sunscreen during the day while using retinoids.
Pro Tip: Start slowly (every other night) if you’re new to retinoids to minimize irritation.
Product Specifications
- Brand: Differin
- Product Type: Topical Acne Treatment
- Available Sizes: 15g (small), 45g (value size)
- Active Ingredient: Adapalene 0.1%
- Texture: Lightweight gel
- Skin Type: Oily, combination, acne-prone skin
- Fragrance-Free: Yes
- Non-comedogenic: Yes
- Dermatologist Developed: Yes
- FDA Approved: Yes
Safety & Precautions
- For external use only
- Avoid contact with eyes, lips, and mouth
- May cause dryness, redness, or peeling in the first few weeks
- Do not use in conjunction with other retinoids or strong exfoliants
- Discontinue use if severe irritation occurs
- Always apply sunscreen during the day
About Differin
Differin is a trusted name in acne care, offering clinically proven solutions developed with dermatologists. Its breakthrough formulations, including the first OTC retinoid, are designed to treat acne at the source for clearer, healthier skin without compromising comfort.
Why Choose Differin Gel?
- Contains dermatologist-recommended Adapalene
- First OTC retinoid treatment in the U.S.
- Clinically proven to reduce acne by up to 87% in 12 weeks
- Gentle formula for long-term use
- Lightweight, fast-absorbing gel
- Non-comedogenic, fragrance-free, and oil-free
Ingredients
Active: Adapalene 0.1% (Acne Treatment)
Inactive: Carbomer 940, PEG-20 Methyl Glucose Sesquistearate, Phenoxyethanol, Propylene Glycol, Methylparaben, Sodium Hydroxide, Purified Water
FAQ
- How long does it take to see results?
You may begin seeing improvement within 2–4 weeks, but full results often take up to 12 weeks. - Can I use it with benzoyl peroxide?
Yes, but not at the same time. Use benzoyl peroxide in the morning and Differin at night. - Will it cause purging?
Some users experience a temporary breakout (purging) as the skin adjusts—this is normal. - Is it safe for sensitive skin?
It’s formulated to be gentle, but those with very sensitive skin should patch test and introduce slowly. - Can I use it for anti-aging?
Yes! Adapalene boosts cell turnover and can help reduce fine lines and improve skin texture over time.
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